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  • Teaching, Tutoring and Training in the Lifelong Learning Sector
    Teaching, Tutoring and Training in the Lifelong Learning Sector

    This core text provides comprehensive support for pre-service and in-service trainee teachers in the Lifelong Learning Sector covering all they need to know to achieve QTLS status. Supporting trainees through all stages of their professional development, the text takes the reader through the theoretical background underpinning teaching and learning and offers practical guidance on day-to-day challenges. This fourth edition has been fully revised and updated and includes a new chapter on teaching practice with notes on observation and lesson planning.New information on behaviour management has been added to support trainees in an aspect of teaching that many find challenging.

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  • Human Epigenetics: How Science Works
    Human Epigenetics: How Science Works

    The view “It’s all in our genes and we cannot change it” developed in the past 150 years since Gregor Mendel’s experiments with flowering pea plants.However, there is a special form of genetics, referred to as epigenetics, which does not involve any change of our genes but regulates how and when they are used.In the cell nucleus our genes are packed into chromatin, which is a complex of histone proteins and genomic DNA, representing the molecular basis of epigenetics.Our environment and lifestyle decisions influence the epigenetics of our cells and organs, i.e. epigenetics changes dynamically throughout our whole life.Thus, we have the chance to change our epigenetics in a positive as well as negative way and present the onset of diseases, such a type 2 diabetes or cancer. This textbook provides a molecular explanation how our genome is connected with environmental signals.It outlines that epigenetic programming is a learning process that results in epigenetic memory in each of the cells of our body.The central importance of epigenetics during embryogenesis and cellular differentiation as well as in the process of aging and the risk for the development of cancer are discussed.Moreover, the role of the epigenome as a molecular storage of cellular events not only in the brain but also in metabolic organs and in the immune system is described. The book represents an updated but simplified version of our textbook “Human Epigenomics” (ISBN 978-981-10-7614-8).The first five chapters explain the molecular basis of epigenetics, while the following seven chapters provide examples for the impact of epigenetics in human health and disease.

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  • Introducing Epigenetics : A Graphic Guide
    Introducing Epigenetics : A Graphic Guide

    Epigenetics is the most exciting field in biology today, developing our understanding of how and why we inherit certain traits, develop diseases and age, and evolve as a species. This non-fiction comic book introduces us to genetics, cell biology and the fascinating science of epigenetics, which is rapidly filling in the gaps in our knowledge, allowing us to make huge advances in medicine.We'll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell. In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.

    Price: 7.99 £ | Shipping*: 3.99 £
  • Epigenetics and Responsibility : Ethical Perspectives
    Epigenetics and Responsibility : Ethical Perspectives

    EPUB and EPDF available Open Access under CC-BY-NC-ND licence. We tend to hold people responsible for their choices, but not for what they can’t control: their nature, genes or biological makeup.This thought-provoking collection redefines the boundaries of moral responsibility.It shows how epigenetics reveals connections between our genetic make-up and our environment.The essays challenge established notions of human nature and the nature/nurture divide and suggest a shift in focus from individual to collective responsibility.Uncovering the links between our genetic makeup, environment and experiences, this is an important contribution to ongoing debates on ethics, genetics and responsibility.

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  • What is epigenetics?

    Epigenetics is the study of changes in gene expression that do not involve alterations to the underlying DNA sequence. These changes can be influenced by various factors such as environment, lifestyle, and aging. Epigenetic modifications can impact how genes are turned on or off, and can have a significant impact on an individual's health and development. Understanding epigenetics is important for gaining insight into how environmental factors can influence gene expression and contribute to various diseases and conditions.

  • Can epigenetics also influence our growth?

    Yes, epigenetics can also influence our growth. Epigenetic changes can affect the expression of genes that are involved in growth and development. For example, epigenetic modifications can regulate the activity of genes that control cell division, differentiation, and tissue growth. These changes can have long-term effects on an individual's growth and development, and can be influenced by environmental factors such as nutrition, stress, and exposure to toxins. Therefore, epigenetics plays a significant role in shaping our growth and development.

  • Can you help me with epigenetics?

    Yes, I can help you with epigenetics. Epigenetics is the study of changes in gene expression that do not involve changes to the underlying DNA sequence. These changes can be influenced by environmental factors, lifestyle choices, and other external stimuli. I can provide information on how epigenetic changes can impact health and disease, as well as the current research and developments in the field. Let me know if you have specific questions or topics you'd like to explore further.

  • Can you give a quick summary of epigenetics?

    Epigenetics is the study of changes in gene expression that do not involve changes to the underlying DNA sequence. These changes can be influenced by various factors such as environment, lifestyle, and aging. Epigenetic modifications can alter how genes are turned on or off, and can have a significant impact on an individual's health and development. Understanding epigenetics is important for gaining insights into how diseases develop and for potentially identifying new therapeutic targets.

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  • Perinatal and Developmental Epigenetics : Volume 35
    Perinatal and Developmental Epigenetics : Volume 35

    Perinatal and Developmental Epigenetics, Volume 32, a new volume in the Translational Epigenetics series, provides a thorough overview of epigenetics in the early developmental and perinatal stages, illuminating pathways for drug discovery and clinical advances.Here, over 25 international researchers examine recent steps forward in our understanding of epigenetic programming during perinatal and early development.The book opens with an in-depth introduction to known and newly discovered epigenetic marks and how they regulate various cellular processes.Later sections examine various prenatal and perinatal environmental experiences and their ability to derail the normal developmental trajectory via epigenetic reprogramming. Insights and suggestions for future research illuminate approaches for identifying individual disease susceptibility.Concluding chapters highlight preventative and targeted therapeutic pathways to improve quality of life into adulthood.

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  • Epigenetics and DNA Damage : Volume 33
    Epigenetics and DNA Damage : Volume 33

    Although scientists recognize the role of epigenetic mechanisms in DNA damage response, the complex, mechanistic interplay between chromatin regulation and DNA repair is still poorly understood.Comprehending how these processes are connected in time and space and play out in developmental processes may reveal novel directions for new research and disease treatment. Epigenetics and DNA Damage, a new volume in the Translational Epigenetics series, offers a thorough grounding in the relationship between DNA Damage, epigenetic modifications, and chromatin regulation.Early chapters address the basic science of DNA damage and its association with various epigenetic mechanisms, including DNA methylation, post-translational histone modifications, histone variants, chromatin remodeling, miRNAs, and lncRNAs.This is followed by a close discussion of DNA damage and epigenetics in metabolism, aging, cellular differentiation, immune function, stem cell biology, and cancer, tying recent research to translational application in disease understanding.Later chapters examine possible epigenetic therapies combining DNA damage induction and epigenetic alteration, as well as instructive chapters on how to analyze DNA damage and epigenetic alterations in new research.

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  • Epigenetics : How Environment Shapes Our Genes
    Epigenetics : How Environment Shapes Our Genes

    The burgeoning new science of epigenetics offers a cornucopia of insights—some comforting, some frightening.For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer.But here’s the good news: unlike mutations, epigenetic effects are reversible.Indeed, epigenetic engineering is the future of medicine.

    Price: 12.99 £ | Shipping*: 3.99 £
  • Genetics and Epigenetics of Breast Cancer
    Genetics and Epigenetics of Breast Cancer

    This book discusses the contribution of genetics and epigenetics alterations in the initiation, development, and recurrence of breast cancer.It also reviews the potential of translating the epigenetic alterations into diagnosis, prognosis, and breast cancer therapy.The initial chapters explore the epigenetics, etiology, and conventional treatment strategies for breast cancer.The subsequent chapters discuss the genetic landscape and cover three main epigenetic modulation mechanisms; histone modification, DNA methylation, and miRNA silencing.Further, the book explores the potential of epigenetic drugs in treating breast cancer.Lastly, it covers the phytochemicals targeting epigenetic modulators in breast cancer treatment.This book is an essential source for researchers and practitioners interested in exploring the potential of epigenetics modulators in breast cancer treatment. ?

    Price: 119.99 £ | Shipping*: 0.00 £
  • What is the difference between gene regulation and epigenetics?

    Gene regulation refers to the mechanisms that control the levels of gene expression, such as turning genes on or off, while epigenetics involves changes in gene expression that are not caused by alterations in the DNA sequence itself. Epigenetic changes can be inherited and are often influenced by environmental factors, whereas gene regulation is more immediate and can be reversible. In summary, gene regulation focuses on the control of gene expression, while epigenetics involves changes in gene expression that are independent of changes in the DNA sequence.

  • Does the zodiac sign have any relationship to epigenetics?

    There is no scientific evidence to suggest that a person's zodiac sign has any relationship to epigenetics. Epigenetics refers to changes in gene expression that are influenced by environmental factors, lifestyle choices, and other external influences, rather than astrological signs. While astrology may have cultural or personal significance for some individuals, it is not considered a valid or reliable factor in determining one's genetic or epigenetic traits.

  • What is the difference between epigenetics and gene regulation?

    Epigenetics refers to the study of changes in gene expression that do not involve alterations to the underlying DNA sequence. These changes can be influenced by environmental factors and can be passed down from one generation to the next. Gene regulation, on the other hand, refers to the mechanisms that control the expression of genes, such as turning them on or off, or increasing or decreasing their expression levels. While epigenetics focuses on the heritable changes in gene expression, gene regulation encompasses the broader set of mechanisms that control gene expression in response to various internal and external signals.

  • Is there any relationship between the zodiac sign and epigenetics?

    There is currently no scientific evidence to suggest a direct relationship between zodiac signs and epigenetics. Epigenetics is the study of changes in gene expression that do not involve alterations to the underlying DNA sequence, while zodiac signs are based on astrological beliefs and do not have a basis in scientific research. Therefore, it is unlikely that there is any connection between the two.

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